(SLE)
BELZUPAKAP SAROTALOKAN(INNC)
MODIFIED HUMAN PAPILLOMAVIRUS (HPV) TYPE 16- DERIVED EMPTY NANOPARTICLE, 55 NM IN DIAMETER CONJUGATED TO APPROXIMATELY 200 MOLECULES OF A PHTHALOCYANINE-BASED PHOTOSENSITIZER (SAROTALOCAN GROUP). EACH NANOPARTICLE IS COMPRISED OF 72 CAPSOMERES, MADE OF 5 MOLECULES OF MODIFIED VIRAL CAPSID PROTEIN L1 [P78>R, T176>N, D273>T, N285>T, S288>N, T353>P, T389>S] AND ONE MOLECULE OF VIRAL CAPSID PROTEIN L2; HUMAN PAPILLOMA VIRUS TYPE 16 (HPV16) CAPSID, A SPHERICAL SHELL OF 72 SELF-ASSEMBLING PENTAGONAL (L1)5(L2)1 CAPSOMERE UNITS COMPRISING THE RECOMBINANT VIRAL CAPSID PROTEINS L1 ([P78>R, T176>N, D273>T, N285>T, S288>N, T353>P, T389>S]-MODIFIED) AND L2, CONJUGATED TO APPROXIMATELY 200 SAROTALOCAN GROUPS (NEAR INFRARED ABSORBING DYE) AT N^6 OF LYSINE RESIDUES; PRODUCED BY HUMAN EMBRYONIC KIDNEY 293 (HEK293) CELLS. PROPOSED INN: LIST 122; REC.INN LIST 84(WHO)
BELZUPACAPUM SAROTALOCANUM(INN)