CANTUZUMABUM MERTANSINUM

Látka

KANTUZUMAB MERTANSIN

CANTUZUMAB MERTANSINE

Informace o látce

INN název: CANTUZUMABUM MERTANSINUM
Český název: KANTUZUMAB MERTANSIN
Anglický název: CANTUZUMAB MERTANSINE
Kód látky: 16962

Synonyma

SB 408075(SLES)HUC242-DM1(SLES)CAS 400010-39-1(CA)CANTUZUMAB MERTANSINE

Přípravky (0)

Žádné přípravky nenalezeny.

(INNE)

CANTUZUMAB MERTANSINE(INNF)

CANTUZUMAB MERTANSINA(INNS)

CANTUZUMAB MERTANSIN(INND)

KANTUZUMAB MERTANSIN(INNC)

IMMUNOGLOBULIN G1-KAPPA, ANTI-[HOMO SAPIENS MUC1 SIALYLATED CARBOHYDRATE, TUMOUR-ASSOCIATED (CA242, CANCER ANTIGEN 242)], HUMANIZED MONOCLONAL ANTIBODY CONJUGATED TO MAYTANSINOID DM1; GAMMA1 HEAVY CHAIN (1-449) [HUMANIZED VH (HOMO SAPIENS IGHV7-4-1*02 (76.50%) -(IGHD)-IGHJ2*01 R120>Q (111), L123>T (114)) [8.8.12] (1-119) - HOMO SAPIENS IGHG1*01 (120-449)], (222-219')-DISULFIDE WITH KAPPA LIGHT CHAIN (1'-219') [HUMANIZED V-KAPPA (HOMO SAPIENS IGKV2-28*01 (82.00%) -IGKJ3*01 V124>L (109), D125>E (110), I126>L (111)) [11.3.9] (1'-112') -HOMO SAPIENS IGKC*01 (113'-219')]; (228-228":231-231")- BISDISULFIDE DIMER; CONJUGATED, ON AN AVERAGE OF 4 LYSYL, TO MAYTANSINOID DM1 [N^2'-DEACETYL-N^2'-(3-MERCAPTO-1-OXOPROPYL)-MAYTANSINE] VIA THE REDUCTIBLE SPP LINKER [N-SUCCINIMIDYL 4-(2-PYRIDYLDITHIO)PENTANOATE](WHO)

CANTUZUMABUM MERTANSINUM(INN)