CANTUZUMABUM RAVTANSINUM

Látka

KANTUZUMAB RAVTANSIN

CANTUZUMAB RAVTANSINE

Informace o látce

INN název: CANTUZUMABUM RAVTANSINUM
Český název: KANTUZUMAB RAVTANSIN
Anglický název: CANTUZUMAB RAVTANSINE
Kód látky: 19499

Synonyma

HUC242-DM4(SLES)IMGN 242(SLES)CAS 868747-45-9(CA)CANTUZUMAB RAVTANSINE

Přípravky (0)

Žádné přípravky nenalezeny.

(INNE)

CANTUZUMAB RAVTANSINE(INNF)

CANTUZUMAB RAVTANSINA(INNS)

CANTUZUMAB RAVTANSIN(INND)

KANTUZUMAB RAVTANSIN(INNC)

IMMUNOGLOBULIN G1-KAPPA, ANTI-[HOMO SAPIENS MUC1 SIALYLATED CARBOHYDRATE, TUMOUR-ASSOCIATED (CA242, CANCER ANTIGEN 242)], HUMANIZED MONOCLONAL ANTIBODY CONJUGATED TO MAYTANSINOID DM4; GAMMA1 HEAVY CHAIN (1-449) [HUMANIZED VH (HOMO SAPIENS IGHV7-4-1*02 (76.50%) -(IGHD)-IGHJ2*01 R120>Q (111), L123>T (114)) [8.8.12] (1-119) -HOMO SAPIENS IGHG1*01 (120-449)], (222- 219')-DISULFIDE WITH KAPPA LIGHT CHAIN (1'-219') [HUMANIZED V-KAPPA (HOMO SAPIENS IGKV2-28*01 (82.00%) -IGKJ3*01 V124>L (109), D125>E (110), I126>L (111)) [11.3.9] (1'-112') -HOMO SAPIENS IGKC*01 (113'-219')]; (228-228":231-231")-BISDISULFIDE DIMER ; CONJUGATED, ON AN AVERAGE OF 3 TO 4 LYSYL, TO MAYTANSINOID DM4 [N2'-DEACETYL-N2'-(4-MERCAPTO-4-METHYL-1-OXOPENTYL)-MAYTANSINE] VIA THE REDUCIBLE SPDB LINKER [N-SUCCINIMIDYL 4-(2- PYRIDYLDITHIO)BUTANOATE], RECOMMENDED INN: LIST 67(WHO)

CANTUZUMABUM RAVTANSINUM(INN)