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COTORETIGEN TOLIPARVOVEC
A REPLICATION-DEFECTIVE ADENO-ASSOCIATED VIRAL VECTOR ENCODING CODON-OPTIMISED HUMAN RETINITIS PIGMENTOSA GTPASE REGULATOR (RPGR). A RECOMBINANT REPLICATION-DEFECTIVE ADENO-ASSOCIATED VIRAL VECTOR SEROTYPE 8 (RAAV8) ENCODING CODONOPTIMISED HUMAN RETINITIS PIGMENTOSA GTPASE REGULATOR (RPGR), UNDER THE CONTROL OF HUMAN RHODOPSIN KINASE (RK) PROMOTER AND BOVINE GROWTH HORMONE POLY(A) SEQUENCE, FLANKED BY AAV2 INVERTED TERMINAL REPEATS (ITR)