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ÉBRIBAFUSP ALFA
CHIMERIC IMMUNOGLOBULIN G4-KAPPA ANTI-(HUMAN COMPLEMENT C3D) FUSED AT THE C-TERMINUS OF THE HEAVY CHAIN, VIA A (G4S)2 PEPTIDE LINKER TO HUMAN COMPLEMENT FACTOR H FRAGMENT, GLYCOFORM ALFA; GAMMA 4 HEAVY CHAIN (1-437) [VH (HOMO SAPIENS IGHV1-46*01 -(IGHD) - IGHJ4*01, CDR-KABAT [5.17.2] (31-35.50-66.99-100)) (1-111) -HOMO SAPIENS IGHG4*01 (CH1 (112-209), HINGE S219>P (210-221), CH2 L226>E (222-331), CH3 M419>L, N425>S (332-436), CHS K438>DEL (437)) (112-437)] FUSED VIA A (G4S)2 PEPTIDE LINKER (438-447) TO HUMAN COMPLEMENT FACTOR H FRAGMENT 1-305 (448-752 IN THE CURRENT SEQUENCE, CONTAINING THE FIRST FIVE CONSENSUS REPEAT SUSHI DOMAINS, RESIDUES 1-304, PLUS THE ADJACENT K^305), (125-219')-DISULFIDE WITH KAPPA LIGHT CHAIN (1'-219') [V-KAPPA (HOMO SAPIENS IGKV2-30*01 -IGKJ4*01, CDR-KABAT [16.7.9] (24'-39'.55'-61'.94'- 102')) (1'-112') -HOMO SAPIENS IGKC*01 (113'-219')]; DIMER (217-217'':220- 220'')-BISDISULFIDE, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, CELL LINE CHO-M, GLYCOFORM ALFA