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EFRANARELAXINA ALFA
EFRANARÉLAXINE ALFA
HUMAN IMMUNOGLOBULIN G1 (IGG1) FC FRAGMENT (H-CH2-CH3-CHS DOMAINS) (1-226) [HOMO SAPIENS IGHG1*03 (HINGE (1-10), CH2 L^14>F, L^15>E, P^111>S (11-120), CH3 S^134>C, T^146>W (121-225), CHS K^227>DEL (226))] FUSED VIA PEPTIDE LINKER (G4S)3G5S (227-247) TO THE CHAIN A OF HUMAN RELAXIN H2 (RLN2) (1-24, 248-271 IN THE ACTUAL SEQUENCE), HETERODIMER (6-6':9-9':134-129':258-257':271- 269')-PENTAKISDISULFIDE WITH HUMAN IMMUNOGLOBULIN G1 (IGG1) FC FRAGMENT (H-CH2-CH3-CHS DOMAINS) (1'-226') [HOMO SAPIENS IGHG1*03 (HINGE (1'-10'), CH2 L^14'>F, L^15'>E, P^111'>S (11'-120'), CH3 Y^129'>C, T146'>S, L^148'>A, Y^187'>V (121'-225'), CHS K^227'>DEL (226'))] FUSED VIA PEPTIDE LINKER (G4S)3G5S (227'-247') TO THE DES- ASP1-CHAIN B OF HUMAN RELAXIN H2 (RLN2) (2-29, 248'-275' IN THE ACTUAL SEQUENCE), PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, CELL LINE CHO-K1, GLYCOFORM ALFA