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LÉPUNAFUSP ALFA
HUMANIZED IMMUNOGLOBULIN G1-KAPPA FAB FRAGMENT (1-226) ANTI-(HUMAN TRANSFERRIN RECEPTOR 1) FUSED VIA PEPTIDYL LINKER ^227GGGGSGGGGSGGGGS^241 TO HUMAN ALFA-L-IDURONIDASE ISOFORM 1 (242-869), (221-219')-DISULFIDE WITH KAPPA LIGHT CHAIN (1'-219'), PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, GLYCOFORM ALFA; IMMUNOGLOBULIN G1-KAPPA, HUMANIZED FAB FRAGMENT TARGETING THE HUMAN TRANSFERRIN RECEPTOR 1 (TFR1), FUSED WITH HUMAN ALFA-L-IDURONIDASE ISOFORM 1, GLYCOFORM ALFA: GAMMA1 HEAVY CHAIN [HOMO SAPIENS IGHV5-51*01; HOMO SAPIENS IGHJ4*01; HOMO SAPIENS IGHG1*01; VH: 1-118; CH1: 119-216; HINGE: 217-226; CDR KABAT H1: NYWLG (31-35); CDR KABAT H2: DIYPGGDYPTYSEKFKV (50-66); CDR KABAT H3: SGNYDEVAY (99-107)] (1-226) FUSED VIA A (G4S)3 PEPTIDE...; PROPOSED INN: LIST 125, RECOMMENDED INN: LIST 87