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MACITEGTAGÉN AUTOLEUCEL
AUTOLOGOUS CD4/CD8 ENRICHED T LYMPHOCYTES DERIVED FROM PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMC) OF PATIENTS BY LEUKAPHERESIS, TRANSDUCED WITH A SELFINACTIVATING, NON-REPLICATING LENTIVIRAL VECTOR ENCODING A A CHIMERIC ANTIGEN RECEPTOR (CAR) TARGETING THE INTERCELLULAR ADHESION MOLECULE-1 (ICAM-1) FUSED TO HUMAN SOMATOSTATIN RECEPTOR TYPE 2 (SSTR2), UNDER CONTROL OF THE HUMAN ELONGATION FACTOR-1 ALPHA (EF-1ALPHA) PROMOTER. A SELF-CLEAVING P2A PEPTIDE SEQUENCE SEPARATES THE TWO TRANSGENES. ... PROPOSED INN: LIST 131, RECOMMENDED INN: LIST 93