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MELREDABLEUKINA ALFA
MELRÉDABLEUKINE ALFA
HUMAN IMMUNOGLOBULIN G1 NON-BINDING VARIANT (HEAVY CHAIN 1-444, L232>A, L233>A, P327>G) FUSED AT THE C-TERMINUS OF THE HEAVY CHAIN VIA PEPTIDYL LINKER 445GGGGSGGGGSGGGGS459 TO HUMAN INTERLEUKIN 2 (1-133, 460-592 IN THE CURRENT SEQUENCE) VARIANT (T3>A462, N88>D547, C125>A584), DIMER, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, GLYCOFORM ALFA;...PROPOSED CORRECTED INN: LIST 126, RECOMMENDED INN: LIST 87
HUMAN IMMUNOGLOBULIN G1 NON-BINDING VARIANT (HEAVY CHAIN 1-444, L^232>A, L^233>A, P^327>G) FUSED AT THE CTERMINUS OF THE HEAVY CHAIN VIA PEPTIDYL LINKER ^445GGGGSGGGGSGGGGS^459 TO HUMAN INTERLEUKIN 2 (1- 33, 460-592 IN THE CURRENT SEQUENCE) VARIANT (T^3>A^462, N^88>D^547, C^125>A^584), DIMER, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, GLYCOFORM ALFA; HUMAN NON-BINDING IMMUNOGLOBULIN G1 KAPPA (IGG1-KAPPA) FUSED VIA A PEPTIDE LINKER TO A MUTATED HUMAN INTERLEUKIN 2 (IL2 MUTEIN): FUSION PROTEIN COMBINING A GAMMA1 HEAVY CHAIN (1-444) [HOMO SAPIENS IGHV3-23*01; HOMO SAPIENS IGHJ4*01; HOMO SAPIENS IGHG1*01; VH: 1-115; CH1: 116-213; HINGE: 214-228; CH2: 229-338 (L^232>A,...; PROPOSED INN: LIST 125