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CAT 8015
MOXÉTUMOMAB PASUDOTOX
IMMUNOGLOBULIN FV FRAGMENT FUSED TO PSEUDOMONAS TOXIN, ANTI- [HOMO SAPIENS CD22 (SIALIC ACID-BINDING IG-LIKE LECTIN 2, SIGLEC-2, SIGLEC2, LEU-14, B-LYMPHOCYTE CELL ADHESION MOLECULE, BL-CAM)], MUS MUSCULUS MONOCLONAL ANTIBODY DISULFIDE STABILIZED FV FRAGMENT WITH THE VARIABLE HEAVY VH DOMAIN FUSED WITH THE TRUNCATED FORM PE38 OF PSEUDOMONAS AERUGINOSA EXOTOXIN A (VH-PE38), DISULFIDE LINKED WITH THE VARIABLE KAPPA DOMAIN (V-KAPPA)]; VH-PE38 (1-476) COMPRISING THE VH DOMAIN (1-123) [METHIONYL -MUS MUSCULUS VH [(IGHV5-12-1*01 -(IGHD)-IGHJ3*01) [8.8.16] (2-123)] FUSED WITH A 7-MER LINKER (124-130) AND WITH THE PSEUDOMONAS AERUGINOSA EXOTOXIN A (ETA) PE38 FRAGMENT (131-476) [277-638 PRECURSOR FRAGMENT WITH DEL 389-405>N (131-476), CONTAINING DOMAIN II (131-243) WITH FURIN PROTEOLYTIC CLEAVAGE SITE (152-164), DOMAIN IB (244-267), DOMAIN III (268-476)], (45-101')-DISULFIDE WITH V-KAPPA (1'-108') [METHIONYL -MUS MUSCULUS V-KAPPA [(IGHKV10- 96*01 -IGKJ1*01) [6.3.9], RECOMMENDED INN: LIST 64