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ALLOGENEIC NATURAL KILLER (NK) CELLS ISOLATED FROM PERIPHERAL BLOOD LEUKAPHERESIS OF INDIVIDUAL DONORS. THE CELLS ARE CO-CULTURED IN MEDIA CONTAINING INTERLEUKIN 15 (IL-15) AND NICOTINAMIDE (NAM, NIACINAMIDE) WITH EXPANSION ENHANCED BY THE PRESENCE OF FEEDER CELLS. THE FINAL CELL POPULATION CONSISTS OF 97-99% CD3-CD56+ NK CELLS, WITH >10% EXPRESSING CD16 (ALSO KNOWN AS FCGAMMARIII) AND CD62L (ALSO KNOWN AS L-SELECTIN) AND WITH CAPACITY TO DEGRANULATE (SURFACE EXPRESSION OF CD107ALPHA [LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1]; >10%), AND TO KILL TARGET CELLS (>10%) IN CO-CULTURE ASSAYS AGAINST HUMAN CANCER CELL LINES.