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HUMANIZED IMMUNOGLOBULIN G1-KAPPA ANTIGEN-BINDING FRAGMENT (FAB), ANTI-[HUMAN TRANSFERRIN RECEPTOR 1 (HTFR, P90, CD71)] FUSED AT THE C-TERMINUS OF THE HEAVY CHAIN VIA A PEPTIDE LINKER TO HUMAN N-SULPHOGLUCOSAMINE SULPHOHYDROLASE (SGSH, SULFOGLUCOSAMINE SULFAMIDASE, SULPHAMIDASE, EC:3.10.1.1); GAMMA 1 HEAVY FAB CHAIN (1-226) [VH (HOMO SAPIENS IGHV5- 51*01 -(IGHD) -IGHJ4*01, CDR-KABAT [5.17.9] (31-35.50-66.99- 107)) (1-118) -HOMO SAPIENS IGHG1*01 (CH1 (119-226)] FUSED VIA PEPTIDE LINKER ^227GGGGSGGGGSGGGGS^241 TO NSULPHOGLUCOSAMINE SULPHOHYDROLASE (1-482, 242-723 IN THE CURRENT SEQUENCE), RESIDUE 291 POSTTRANSLATIONALLY MODIFIED TO FORMYLGLYCINE (FGLY), (221-219')-DISULFIDE WITH KAPPA LIGHT CHAIN (1'- 219') [V-KAPPA (HOMO SAPIENS IGKV2D-29*02 -IGKJ1*01, CDRKABAT [16.7.9] (24'-39'.55'-61'.94'-102')) (1'-112') -HOMO SAPIENS IGKC*01 (113'-219')]; NON-COVALENT DIMER, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, CELL LINE CHO-K1, GLYCOFORM ALFA