CAS 407492-04-9(CA)RONEPARSTAT(INNE)RONÉPARSTAT(INNF)RONEPARSTAT
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(INNS)
RONEPARSTAT(INNC)
HEPARAN SULFATE MIMETIC COMPOUND THAT IS OBTAINED BY N-DES-SULFO AND N-ACETYL REACTIONS ON HEPARIN FROM PORCINE INTESTINAL MUCOSA, SODIUM PERIODATE GLYCOL SPLIT OXIDATION OF URONIC ACIDS ELEMENTS AND SODIUM BOROHYDRIDE REDUCTION OF ALDEHYDES PRODUCED DURING OXIDATION; THE MAJORITY OF THE COMPONENTS HAVE A GLUCURONIC ACID (COMING FROM THE HEPARIN STARTING MATERIAL) AND GLUCOSAMINE (FORMED VIA DECOMPOSITION OF THE GLUCURONIC ACID) STRUCTURE AT THE NONREDUCING END AND IDURONIC ACID 2-SULPHATE OR GLYCOL SPLIT STRUCTURE AT THE REDUCING END OF THEIR CHAIN; THE AVERAGE MOLECULAR WEIGHT RANGE IS 15000 TO 25000 DA; THE DEGREE OF GLYCOL SPLIT IS ABOUT 25% [M/(N+M)] AND THE DEGREE OF SULFATATION IS ABOUT 1.2 PER DISACCHARIDIC UNIT(WHOM)