(INNS)
ROSNILIMAB(INNC)
IMMUNOGLOBULIN G1-KAPPA, ANTI-[HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD-1, PD1, CD279)], HUMANIZED MONOCLONAL ANTIBODY; GAMMA1 HEAVY CHAIN HUMANIZED (1-451) [VH (HOMO SAPIENS IGHV7-4-1*02 (87.8%) -(IGHD) -IGHJ4*01 (92.3%) L123>T (116), CDR-IMGT [8.8.14] (26-33.51- 58.97-110)) (1-121) -HOMO SAPIENS IGHG1*01 (100%), G1M17,1 (CH1 K120 (218) (122-219), HINGE 1-15 (220-234), CH2 (235-344), CH3 D12 (360), L14 (362) (345-449), CHS (450-451)) (122-451)], (224-215')- DISULFIDE WITH KAPPA LIGHT CHAIN HUMANIZED (1'-215') [VKAPPA (HOMO SAPIENS IGKV3D-11*02 (86.8%) - IGKJ4*01 (100%), CDR-IMGT [7.3.9] (27-33.51-53.90- 98)) (1'-108') -HOMO SAPIENS IGKC*01 (100%), KM3 A45.1 (154), V101 (192) (109'-215')]; DIMER (230- 230'':233-233'')-BISDISULFIDE, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, CELL LINE CHO-K1, GLYCOFORM ALFA(WHO)
ROSNILIMABUM(INN)