(SLE)
SABATOLIMAB(INNC)
IMMUNOGLOBULIN G4-KAPPA, ANTI-[HOMO SAPIENS HAVCR2 (HEPATITIS A VIRUS CELLULAR RECEPTOR 2, T-CELL IMMUNOGLOBULIN MUCIN FAMILY MEMBER 3, TIM-3, TIM3, TIMD3, CD366)], HUMANIZED MONOCLONAL ANTIBODY; GAMMA4 HEAVY CHAIN HUMANIZED (1-444) [VH (HOMO SAPIENS IGHV1-46*01 (87.8%) -(IGHD) -IGHJ4*01 (92.3%)) CDR-IMGT [8.8.11] (26-33.51-58.97-107) (1- 118)-HOMO SAPIENS IGHG4*01, G4V5 H P10 (CH1 (119- 216), HINGE 1-12 S10>P (226) (217-228), CH2 (229- 338), CH3 (339-443), CHS K>DEL (444)) (119-444)], (132-218')-DISULFIDE WITH KAPPA LIGHT CHAIN HUMANIZED (1'-218') [V-KAPPA (HOMO SAPIENS IGKV1-39*01 (81.6%) -IGKJ4*01 (100%)) CDR-IMGT [10.3.9] (27- 36.54-56.93-101) (1'-111') -HOMO SAPIENS IGKC*01 (100%), KM3 A45.1 (157), V101 (195) (112'-218')]; DIMER (224-224":227-227")-BISDISULFIDE, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, GLYCOFORM ALFA(WHO)
SABATOLIMABUM(INN)