TENVUMESTROCEL(INNE)TENVUMESTROCEL(CZ)ALLOGENEIC HUMAN MESENCHYMAL STROMAL CELLS DERIVED FROM UMBILICAL CORD BLOOD (HUCB-MSCS). THE CELLS ARE ISOLATED BY DENSITY-GRADIENT CENTRIFUGATION AND EXPANDED BY SUB-CULTURING OF THE ADHERENT CELL POPULATION. CELLS (ON AVERAGE > 95%) EXPRESS MESENCHYMAL STROMAL CELL RELATED ANTIGENS (CD105 AND CD73). THE CELLS ARE ALSO POSITIVE FOR THE CD29 ANTIGEN (INTEGRIN BETA-1), THE CD44 ANTIGEN (CELL ADHESION GLYCOPROTEIN), THE CD13 AND CD90 ANTIGENS, AND THE HLA-ABC HISTOCOMPATIBILITY ANTIGEN. CELLS DO NOT EXPRESS (ON AVERAGE < 1%) HEMATOPOIETIC ANTIGENS (CD45, CD34 AND CD14), HISTOCOMPATIBILITY ANTIGEN (HLADR), ENDOTHELIAL CELL ANTIGEN (CD31), OSTEOCLAST ANTIGEN (CD51/61), AND CD64; REC. LIST 85