(SLE)
TIFALIBEP(INNC)
FUSION PROTEIN COMPOSED OF 3 BINDING DOMAINS, EACH CONSISTING OF A THREE-ALPHA-HELIX MOTIF DERIVED FROM THE IMMUNOGLOBULIN (IG)-BINDING Z-DOMAIN OF STAPHYLOCOCCAL PROTEIN A (SPA), ENGINEERED FOR BINDING TO THE HUMAN NEONATAL FC RECEPTOR (FCRN) WITH THE TWO IDENTICAL N- AND CTERMINAL DOMAINS (1-58, 116-173), AND FOR BINDING TO THE DOMAIN II OF HUMAN SERUM ALBUMIN (HSA) WITH THE CENTRAL DOMAIN (59-110), CONNECTED VIA A G4S PEPTIDE LINKER (111- 115); [FCRN-BINDING ENGINEERED SPA PEPTIDE (1-58)]-[HSABINDING ENGINEERED SPA PEPTIDE (59-110)]-[G4S LINKER (111- 115)]-[FCRN-BINDING ENGINEERED SPA PEPTIDE (116-173] FUSION PROTEIN; PRODUCED IN ESCHERICHIA COLI(WHO)
TIFALIBEPUM(INN)