(SLE)
TILOGOTAMAB(INNC)
IMMUNOGLOBULIN G1-KAPPA, ANTI-[HOMO SAPIENS TNFRSF10B (TUMOR NECROSIS FACTOR RECEPTOR (TNFR) SUPERFAMILY MEMBER 10B, DEATH RECEPTOR 5, DR5, TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTOR 2, TRAILR2, TRAIL-R2, TR-2, CD262)], HUMANIZED MONOCLONAL ANTIBODY; GAMMA1 HEAVY CHAIN HUMANIZED (1-447) [VH (HOMO SAPIENS IGHV1-3*01 (84.7%) -(IGHD) -IGHJ4*01 (93.3%)) CDR-IMGT [8.8.11] (26-33.51-58.97-107) (1-118) -HOMO SAPIENS IGHG1*03, G1M3, NG1M1, G1V34 CH3 G109 (CH1 R120 (215) (119-216), HINGE 1-15 (217-231), CH2 (232-341), CH3 E12 (357), M14 (359), E109>G (431) (342-446), CHS K>DEL (447)) (119-447)], (221-213')-DISULFIDE WITH KAPPA LIGHT CHAIN HUMANIZED (1'-213') [V-KAPPA (HOMO SAPIENS IGKV1-16*01 (83.2%) -IGKJ4*01 (100%)) CDR-IMGT [5.3.9] (27-31.49-51.88- 96) (1'-106') -HOMO SAPIENS IGKC*01 (100%) KM3 A45.1 (152), V101 (190) (107'-213')]; DIMER (227-227":230-230")-BISDISULFIDE, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, GLYCOFORM ALFA(WHO)
TILOGOTAMABUM(INN)