(INND)
TORULIMOGEN LONFERENCEL(INNC)
IRRADIATED HUMAN EMBRYONIC KIDNEY CELLS (CELL LINE HEK293) TRANSFECTED WITH THREE SELF-INACTIVATING, NON-REPLICATING LENTIVIRAL VECTORS INDIVIDUALLY EXPRESSING (I) CODON-OPTIMISED WILMS TUMOUR PROTEIN 1 (WT1) ISOFORM D, (II) CODON-OPTIMISED CLUSTER OF DIFFERENTIATION 1D (CD1D), AND (III) A CODON-OPTIMISED REVERSE TETRACYCLINE-CONTROLLED TRANSACTIVATOR (RTTA), A FUSION PROTEIN OF THE TETR REPRESSOR AND THE HERPES SIMPLEX VIRUS VP16 TRANSACTIVATION DOMAIN. EXPRESSION OF BOTH CD1D AND RTTA IS CONTROLLED BY THE CYTOMEGALOVIRUS IMMEDIATE EARLY (CMV IE) PROMOTER; EXPRESSION OF WT1 IS CONTROLLED BY AN INDUCIBLE TET RESPONSIVE PROMOTER (TRE). EACH LENTIVIRUS VECTOR ALSO CONTAINS A PACKAGING SIGNAL (PSI), A REV-RESPONSE ELEMENT (RRE), ... PROPOSED INN: LIST 127, RECOMMENDED INN: LIST 89(WHO)
TORULIMOGENUM LONFERENCELUM(INN)