ALLOGENEIC T LYMPHOCYTES OBTAINED FROM PERIPHERAL BLOOD MONONUCLEAR CELLS BY LEUKAPHERESIS OF HEALTHY DONORS, ELECTROPORATED WITH CRISPR/CAS9 (CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS/ CRISPR-ASSOCIATED PROTEIN 9) HYBRID RNA-DNA NUCLEOPROTEIN COMPLEXES TO KNOCK OUT THE T CELL RECEPTOR ALPHA CHAIN CONSTANT (TRAC) AND PROGRAMMED CELL DEATH PROTEIN 1 (PDCD1) GENES AND TRANSDUCED WITH A RECOMBINANT ADENO-ASSOCIATED VIRUS VECTOR SEROTYPE 6 (AAV6) VECTOR TO INTRODUCE AN ANTI-CD19 CHIMERIC ANTIGEN RECEPTOR (CAR) EXPRESSION CASSETTE AT THE TRAC LOCUS BY HOMOLOGY-DIRECTED REPAIR. ... PROPOSED INN: LIST 131, RECOMMENDED INN: LIST 93(WHO)